Letrozole Drug Description

Letrozole is an oral medication primarily used in the treatment of certain types of breast cancer in postmenopausal women. It belongs to a class of drugs known as aromatase inhibitors, which work by reducing estrogen levels in the body.

Mechanism of Action

The primary function of letrozole is to inhibit the aromatase enzyme, which is crucial for the synthesis of estrogen from androgens. By lowering estrogen levels, letrozole helps stop the growth of hormone-sensitive tumors.

Indications

• Treatment of hormone receptor-positive breast cancer in postmenopausal women.
• Adjuvant therapy following surgery in early-stage breast cancer.
• Treatment for advanced breast cancer that has progressed after anti-estrogen therapy.

Dosing Information

The typical dosage of letrozole varies based on the individual patient’s condition but Femara 2,5 mg ACA Müller drug description generally includes:

1. 2.5 mg once daily, taken orally.
2. Dosage adjustments may be necessary for specific patient populations.

Side Effects

• Hot flashes
• Joint pain or stiffness
• Fatigue
• Nausea
• Bone density loss

Precautions and Contraindications

Before using letrozole, patients should consider the following precautions:

• Not recommended for use in premenopausal women.
• Patients with liver disease should consult their healthcare provider before starting therapy.
• Monitoring bone health is crucial due to the risk of osteoporosis.

Frequently Asked Questions (FAQs)

1. How long do I need to take letrozole?

The duration of treatment may vary, typically lasting for 5 years, but should always be determined by a healthcare professional based on individual circumstances.

2. Can letrozole be taken with other medications?

Patients should inform their healthcare providers about all medications they are taking, including over-the-counter drugs and supplements, to avoid potential interactions.

3. What should I do if I miss a dose?

If a dose is missed, take it as soon as remembered. However, if it’s close to the time for the next dose, skip the missed dose and resume the regular schedule. Do not double up on doses.

Conclusion

In summary, letrozole serves as a vital medication in the fight against certain types of breast cancer. Understanding its mechanism, uses, and potential side effects can help patients make informed decisions in collaboration with their healthcare providers.